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Our Impact

Children's Hospital Oakland Research Institute (CHORI) is the internationally renowned biomedical research institute of UCSF Benioff Children's Hospital Oakland. With over 350 world-class scientists and an annual budget of over $50 million, CHORI was most recently ranked in the top 10 in the nation for National Institutes of Health pediatric research funding. Please refer to our 2011 CHORI Annual Report (PDF) for a closer look at our institute.

Bridging basic science and clinical research in the treatment and prevention of human disease, Children's Hospital Oakland Research Institute is a leader in translational research. During the last 50 years, CHORI has provided cures for debilitating blood diseases and cancers, developed new vaccines for infectious diseases, and discovered new treatment protocols for previously fatal or debilitating conditions.

Accomplishments

  • Children with blood disease and cancers cured through our innovative transplantation research program.
  • The 1st cure of alpha thalassemia major in North America.
  • The world's most comprehensive sickle cell disease and thalassemia centers.
  • The largest global resource of recombinant DNA libraries.
  • The world's only non-profit sibling donor cord blood program.
  • Established the Children's Global Health Initiative, bringing together the worlds leading medical and scientific minds to collaborate in alleviating the suffering of the world's children.

CHORI Centers of Research

Providing the highest standard of excellence and innovation, CHORI brings together a multidisciplinary collaborative of distinguished investigators in eight different Centers of Research: CHORI's eight research centers are part of a comprehensive approach to pediatric research and development.
  • The Cancer Center is dedicated to the prevention, diagnosis, and treatment of pediatric cancers.
  • The Genetics Center seeks to better understand the genetic basis of disease, as well as how to manage and prevent these types of ailments.
  • The Immunology and Vaccine Development Center is an ongoing program that helps develop new vaccines and make them accessible to those in need.
  • The Nutrition and Metabolism Centeris committed to understanding how metabolism and nutrition lead to health problems currently facing a large portion of the population.
  • The Obesity, Cardiovascular Disease and Diabetes Prevention Center offers a multidisciplinary approach to health and wellness, bringing together top researchers from several different fields all working toward a common goal.
  • The Sickle Cell and Thalassemia Center operates on both a national and international level, reaching out to explore new and novel treatments that can make a real impact on global health.
  • The Newborn and Pediatric Critical Care Center is dedicated to improving how we care for critically ill infants and children. The Center initiates studies designed to improve the outcome of preemies, babies, and children with severe respiratory failure, or who have vulnerable or injured brains.
  • The Jordan Family Center for Bone Marrow Transplantation and Cellular Therapies Research is an endowed program focused on expanding the science of regenerative medicine. Together, experts in cell biology, medicine, and medical technology advance revolutionary therapies that use human cells to treat and cure disease.

Among the leading biotech enterprises in the Bay Area, CHORI has had over 86 patents issued and over 200 inventions disclosed. In addition to providing world-class research, CHORI is also a teaching institute, offering unique educational opportunities to high school, college, doctoral and post-doctoral students. A collaborative nexus for innovative research and learning with global impact, CHORI is at the forefront of basic and clinical research that strives to change the world one patient at a time.

Please visit the CHORI Timeline for a snapshot of CHORI's accomplishments during the last half century.